WVU Research Corporation Research Lab Manager in Morgantown, West Virginia
Description Purpose This position will support the Auditory Development and Connectomics Laboratory by providing oversight of laboratory activities. The ADCL studies the development and mature structure and function of auditory neural circuits using a range of technologies. These include brain slice cellular biophysics, gene expression and manipulation, confocal and super-resolution light microscopy, high resolution reconstruction and analysis of neural wiring diagrams (connectomes), and computational modeling of neural circuits. This work utilizes a variety of mouse models and manipulation of gene expression using stereotaxic injection of chemical and viral vectors.
This position provides program, as well as direct internal and external client support services. Responds to inquiries and resolves matters of low to moderate complexity. Responsibilities require general theoretical knowledge, as well as some judgement, resourcefulness and originality. Diverse guides and precedents are available to apply or adapt to the circumstances. Work effort has considerable impact on client services, program and project image with potential legal liabilities.
Duties & Responsibilities Responsibilities are functional in nature, and performed under general supervision. Specific tasks include, but are not limited to: 1) Manage animal colony, including regular census and breeding schedules and genotyping of transgenic mouse lines. 2) Conduct histological and imaging procedures that are standard in the laboratory, including tissue preparation for electron, confocal and super-resolution microscopy. 3) Maintain laboratory supply inventory. 4) Conduct surgical procedures, such as transcardial perfusion and stereotaxic injections. 5) Perform imaging including confocal and super-resolution imaging. 6) Prepare solutions and materials for laboratory experiments. 7) Oversee other members of the laboratory with their experiments, as needed. 8) Perform tissue culture, immunohistochemistry, and/or molecular biology experiments under the direction and supervision of the PI. 9) Keep detailed records of personal research data, written and electronic logs of mouse colony censuses, material safety data sheets, and chemical inventories. 10) Oversee timely submission of regulatory forms, including animal use protocols. 11) Document, analyze, and present experimental results and discuss findings. 12) Set up, adjust, calibrate, clean, maintain, and troubleshoot laboratory equipment. 13) Assist with training of new lab personnel, when needed. Sharing of knowledge with other lab personnel is expected.
Supervisory/Lead Role Position reports to the Principal Investigator. Normally receives general instructions on routine work and detailed instructions on new assignments. Will receive guidance when a difficulty arises in a current project or situation. May offer input on determining methods or procedures. General sharing of knowledge and team participation is expected in this role. Program, project or activity lead and work coordination may be assigned in this position.
Physical Demands Manual dexterity for day-to-day operations of computers and other lab equipment, including stereo and compound microscopes, is required. Mental dexterity to focus on experimental protocols. This position requires skill and accuracy in actions required to perform and use all laboratory equipment (such as computers, printers, copiers, centrifuges, autoclaves, etc.), as well as a high degree of exactness in the use of hand instruments (pippettors, dissecting tools, syringes, etc.). Requires sitting, walking, standing, bending, and lifting or moving of equipment or machinery (using a dolly) up to 75 pounds. Routine handling of mice is required.
Work Environment Work will be performed in a standard laboratory environment including using computers and laboratory equipment with electrical connections. The incumbent must comply with all laboratory safety procedures and clothing/equipment requirements. Exposure to laboratory animals and biological samples is expected; however, protective measures will be provided. All University safety courses and training sessions will be completed by the technician. Incumbent may experience the following and require medical monitoring: a) Animal Contact - direct exposure to vertebrate animals, animal tissues or research with body fluids or wastes; b) Contacting Hazardous Chemicals –daily or weekly, using strong acids or caustics, fuel or tar products or cancer causing chemicals; c) Human Pathogen and Biological Research (BSL2+/3)- for those working with or in proximity to certain biological agents; d) Respirator Use (Voluntary)- for individuals who wear disposable masks or medical procedure masks; e) Scientific Research- research with nanoparticles, lasers, anesthetic, fuels or mining, aquatic or diving etc.
Requirements Requisite Qualifications Education and/or Experience 1) Master’s degree in biology, or a related science field; And 2) 2 – 4 years of experience with animal colony management and histological procedures; Or 3) An equivalent combination of education and experience.
Skills, Knowledge, Abilities 1) Ability to train and oversee new lab personnel. 2) Knowledge of mouse handling, molecular biology, tissue culture, or immunocytochemistry skills. 3) Ability to work with mice in a laboratory setting. 4) Strong verbal and written communication. 5) Strong time management, organizational, and self-motivation skills. 6) Skilled at using scientific rules and methods to solve problems. 7) Knowledge of the use and preparation of cell culture media, aseptic technique, general microbiological procedures, and relevant molecular biology protocols. 8) Knowledge of general laboratory terminology. Knowledge of medical terminology would be helpful. 9) Ability to measure volumes and/or weights of chemicals, and apply mathematical concepts to calculate concentrations (in molar units) and prepare solutions according to precise specifications. 10) Ability to operate general laboratory equipment (pH meter, scales, pipetmen, centrifuges, PCR machine, etc.), and the willingness and ability to learn new techniques, procedures, or protocols and apply them in an appropriate manner. 11) Skilled at gathering, understanding and implementing technical protocols from current literature. 12) Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. 13) Ability to follow oral and written instructions, and apply common sense understanding to carry out instructions furnished in written, oral, or diagram form. 14) Ability to maintain records and inventories 15) Ability to write routine reports and correspondence. 16) Ability to use tools including wrenches to perform assembly or standard mechanical repairs of laboratory equipment.
Behavioral Competencies 1) Technical skills – Strives to continuously build knowledge and skills; pursues training and development opportunities; assess strengths, weaknesses, and shares expertise with others. 2) Problem solving – Gathers and analyzes information, identifies problems, develops alternatives, uses reason even when dealing with emotional topics and works well in groups and resolves matters timely. 3) Internal & External Customer Service – Manages difficult or emotional matters with objectivity and openness; responds promptly to needs and requests for service and assistance; meets commitments and dates, notifies others if change occurs; provides, solicits and applies feedback; and builds goodwill through balanced contributions, positive approach, respect and support of others. 4) Communications – Demonstrates group presentation skills, participates in meetings, listens and gets clarification, is responsive and speaks clearly and persuasively in positive and negative situations. Writes and edits clearly and informatively, varies style to meet needs, presents numerical data effectively, and able to read and interpret written information. 5) Organizational Support – Aligns work and develops strategies to meet organizational goals; seeks to improve and promote quality; demonstrates accuracy and thoroughness; and upholds organizational expectations and values. 6) Self-Management – Responds to management direction; resourcefully adapts to changes in work environment and circumstances; responds well under pressure and manages competing demands; takes calculated risks, asks for and offers help when needed; exercise discretion and sound judgment; is tactful and responsible for own actions. Adheres to work schedule and complies with leave management responsibilities.
Requisition Number: 16-0062
Post Date: 5/6/2016
Title: Research Lab Manager
Position Type: Full Time
Work Hours: 40